Prof.Dr. Belkıs ATASEVER ARSLAN

MDBF / Bölüm Başkanı - Moleküler Biyoloji ve Genetik (Türkçe)

belkis.arslanuskudar.edu.tr

(0216) 400 22 22 / 2602

ORCID: 0000-0001-5827-8484

Documents : 37 | Citation : 533 | h-index : 14

Citation : 807 | h-index : 15 | i10-index : 19

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Araştırma Alanları

Fizyoloji, İmmunoloji, Sinyal Transdüksiyonu

Araştırma Alanları İle Örtüşen BM Sürdürülebilir Kalkınma Hedef Etiketleri

3

Kısa Özgeçmiş

Doç.Dr. Belkıs Atasever Arslan 1980 yılında İstanbul’da doğdu. 2001 yılında İstanbul Üniversitesi Biyoloji bölümü bitirmiştir. İstanbul Üniversitesi, İstanbul Tıp Fakültesi Fizyoloji Anabilim dalında 2004 yılında yüksek lisans derecesini, 2008 yılında doktora derecesini almıştır.
2009 yılında Türkiye Bilimler Akademisi (TÜBA) tarafından Türkiye’de doktora sonrası araştırmacı bursu kazanan 3 araştırmacıdan biridir. Aynı yıl Tübitak tarafından da burs kazanmış ve Sabancı Üniversitesi, Biyolojik Bilimler ve Biyomühendislik programında 3 yıl post doktora yapmıştır.
Üsküdar Üniversitesi’nde 2012 yılında yardımcı doçent olarak çalışmaya başlamıştır. 2018 yılında Tıp-Fizyoloji alanında Doçent ünvanı almıştır. 2019 yılında University of Illinois at Chicago, Tıp Fakültesi, Anatomi ve Hücre Biyolojisi bölümüne, Adjunct Associate Professor olarak atanmıştır. 2 Avrupa patent tescili ve çeşitli patent başvuruları bulunmaktadır. İlaç keşfi, immünoloji ve sinyal transdüksiyonu konularında çalışmalar yapmaktadır.
Evli ve 2 çocuk annesidir.

Devamı

Öğrenim Durumu & Akademik Unvanlar

2001

Lisans

İstanbul Üniversitesi Biyoloji

2004

Yüksek Lisans

İstanbul Üniversitesi, İstanbul Tıp Fakültesi Fizyoloji

2008

Doktora

İstanbul Üniversitesi, İstanbul Tıp Fakültesi Fizyoloji


Doçentlik

Üsküdar Üniversitesi Sağlık Bilimleri-Fizyoloji

2018

Profesörlük

Üsküdar Üniversitesi Fizyoloji

2023

Yönetilen Lisansüstü Tezleri

  1. Sesamolün Kan-Beyin Bariyerinde Sigara Dumanı Toksisitesine Karşı Koruyucu Etkilerinin Araştırılması, 2024.
  2. ARPE-19 hücrelerinde yüksek glikoza karşı FPS-ZM1 ve trans-anetolün yara iyileşme üzerine etkisi, 2024.
  3. Kuarsetin, Berberin, Saponin ve Krisin Moleküllerinin Akciğer Kanser Hücrelerinde Antikanser Etkisinin Araştırılması ve Etkilediği Sinyal Yolaklarının Belirlenmesi, 2020.
  4. Alzheimer hastalığında PSMD9 gen polimorfizmi, 2019.
  5. Otistik Spektrum Bozukluğunun Genetik Altyapısının ve Moleküler Sinyal Yolakların Araştırılması., 2016.

Akademik Faaliyetler > Yayınlar

(Scopus) Toplam: 42

A square planar cobalt(II)-thiosemicarbazone complex. Synthesis, characterization, antiviral and anti-inflammatory potential

Journal of Molecular Structure (2025)

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Protective effects of sesamol against cigarette smoke toxicity on the blood-brain barrier

BMC Complementary Medicine and Therapies (2025)

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Gene expression analysis in plasma of patients with Alzheimer's disease

Neuroscience Research Notes (2024)

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Effects of Vaccinium myrtillus L. Extract on TNF-α-induced Inflammation through Human Paraoxonases

Roumanian Journal of Chemistry (2023)

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Selective cytotoxicity of chemical composition of Spirulina platensis extract in endometrial cells: In vitro and in silico approach

Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi (2023)

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Synthesis, SARS‐CoV‐2 3CL main protease inhibitor, anti‐inflammatory and wound healing effects of a zinc(II)‐thiosemicarbazone complex

Applied Organometallic Chemistry (2023)

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Chemical Constituent of Isochrysis galbana Microalgae Extract And Its Cytotoxic Activities On Leukemic Cell Lines

İstanbul Journal of Pharmacy (2022)

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Differential CTCF binding in motor neurons and lymphocytes

F1000Research (2021)

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The iron(III) and nickel(II) complexes with tetradentate thiosemicarbazones. Synthesis, experimental, theoretical characterization, and antiviral effect against SARS-Cov2

Journal of Molecular Structure (2021)

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Tumor necrosis factor alpha gene rs1799724 polymorphism in Alzheimer’s disease

General physiology and biophysics (2020)

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Immunotherapy Approaches on Innate Immunity for SARS-Cov2

Acta virologica (2020)

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Bioelectricity generation using human neuronal-like cells in single chamber biofuel cells

Journal of Cleaner Production (2020)

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Proteasome modulator 9 (PSMD9) gene rs14259 polymorphism in Alzheimer’s disease

Bratislava Medical Journal (2020)

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Proteasome modulator 9 gene rs14259 polymorphism in patients with diabetic polyneuropahy

Archives of Neuropsychiatry (2019)

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Rabies Virus 31D Peptide‐[P(VP‐co‐AA)] Conjugates: Synthesis, Characterization and Cytotoxicity Evaluation

CHEMISTRYSELECT (2019)

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Synergistic effects of quercetin and selenium on oxidative stress in endometrial adenocarcinoma cells

Bratislava Medical Journal (2019)

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Synergistic effects of quercetin and selenium on oxidative stress in endometrial adenocarcinoma cells.

Bratislava Medical Journal (2019)

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Androgen Receptor (NR3C4) regulator potential of Ceratonia siliqua extract and its signaling pathways

PHARMACOGNOSY MAGAZINE (2018)

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Chemical and molecular characterization of metabolites from Flavobacterium sp.

PLOS ONE (2018)

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Apoptotic effect of Nigella sativa on human lymphoma U937 cells

Pharmacognosy Magazine (2017)

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Dinutuximab in the Treatment of High-Risk Neuroblastoma in Children

CLINICAL MEDICINE INSIGHTS-THERAPEUTICS (2017)

Apoptotic mechanisms of nickel(II) complex with N1-acetylacetone-N4-4-methoxy-salicylidene-S-allyl-thiosemicarbazone on HL60 leukemia cells

GENERAL PHYSIOLOGY AND BIOPHYSICS (2016)

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Potential of GRID2 receptor gene for preventing TNF-induced neurodegeneration in autism

NEUROSCIENCE LETTERS (2016)

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High Plasma Pentraxin 3 Levels in Diabetic Polyneuropathy Patients with Nociceptive Pain.

The Tohoku Journal of Experimental Medicine (2016)

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Screening of new antileukemic agents from essential oils of algae extracts and computational modeling of their interactions with intracellular signaling nodes

European Journal of Pharmaceutical Sciences (2016)

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The effect of saffron (its active constituent, crocin) on the cardiovascular complication and dyslipidemia in streptozotocin induced diabetic rats

African Journal of Traditional, Complementary and Alternative Medicines (2015)

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Recently Emerging Signaling Landscape of Ataxia-Telangiectasia Mutated (ATM) Kinase

Asian Pacific Journal of Cancer Prevention (2014)

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Effects of Micro Environmental Factors on Natural Killer Activity NK of Beta Thalassemia Major Patients

Cellular Immunology (2013)

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CD8 lineage-specific regulation of interleukin-7 receptor expression by the transcriptional repressor Gfi1

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

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Decreased IFN-γ and IL-12 levels in panic disorder

Journal of Psychosomatic Research (2012)

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Chemical constituents of the different parts ofColchicum baytopiorumand their cytotoxic activities on K562 and HL60 cell lines

Pharmaceutical Biology (2009)

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Cytotoxic activities of new iron(III) and nickel(II) chelates of some S-methyl-thiosemicarbazones on K562 and ECV304 cells

Investigational New Drugs (2009)

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Synthesis, Characterization and Cytotoxic Properties of Pd(II), Cd(II) and Hg(II) Complexes of 2-Amino-5-Chloro-Benzophenone-4-(H/Ph)-Thiosemicarbazones

Main Group Metal Chemistry (2008)

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Synthesis, characterisation and cytotoxic properties of the N1,N4-diarylidene-S-methyl-thiosemicarbazone chelates with Fe(III) and Ni(II)

European Journal of Medicinal Chemistry (2006)

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IN VITRO EFFECTS OF VITAMIN C AND SELENIUM ON NK ACTIVITY OF PATIENTS WITH β -THALASSEMIA MAJOR

Pediatric Hematology and Oncology (2005)

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Effects of flavonoids obtained from Cynara syriaca on leukemic cells

Ankara Universitesi Eczacilik Fakultesi Dergisi (2003)

Akademik Faaliyetler > Yayınlar

(Diğer Bilimsel Yayınlar) Toplam: 18

Anti-diabetic Effects of Berberis cretica Extract in INS-1E Cells

International Journal of Science Letters (2021)

Does Radiotherapy Augment Natural Killer Cell Function in Pediatric Acute Lymphoblastic Leukemia?

Istanbul University Institute of Health Sciences Journal of Advanced Research in Health Sciences (2021)

Akademik Faaliyetler > Kitap - Kitap Bölümü

(Diğer) Toplam: 3
  1. Bölüm : Hücre altı düzeyde akson ve dendrit tipleri, fonksiyonel özellikleri (Fonksiyonun Cerrahi Anatomisi), Pınar Öz, Belkıs Atasever Arslan, , US Akademi, 2019
  2. Nöron ve nöroglianın tipleri, histopatolojik özellikleri (Fonksiyonun Cerrahi Anatomisi), Belkıs Atasever Arslan, , Intertıp Yayınevi, 2018
  3. Hücre altı düzeyde protein sentezi, hücre iskeleti oluşumu ve fonksiyonel özellikleri (Fonksiyonun Cerrahi Anatomisi), Belkıs Atasever Arslan, Kaan YilancioĞlu, , Intertıp Yayınevi, 2018

Akademik Faaliyetler > Editörlük

  1. Turkish Journal of Biology, ISBN:1300-0152, 2022.

Projeler > Projeler

  1. Sesamolün Kan-Beyin Bariyerinde Sigara Dumanı Toksisitesine Karşı Koruyucu Etkisinin Araştırılması, 2025.
  2. Bakır (Iı) Ve Ph Kombinasyonunun, Amiloid R (AR) Plak Oluşumunda "Self Assembly" Mekanizmalarına Etkisinin Araştırılması., 2024.
  3. Tetradentat tiyosemikarbazon ligandı taşıyan kobalt (II) ve çinko (II) komplekslerinin antiviral ve antiinflamatuvar etkilerinin araştırılması, 2024.
  4. Betainin Kronik Myeloid Lösemi Hücrelerinde Antikanser Etkisinin Araştırılması ve Sinyal Yolaklarının Belirlenmesi., 2023.
  5. Sigara dumanı ekstresinin endotel hücrelerinde adezyon molekülleri ve sinyal yolakları üzerine etkisinin sesamol ile modülasyonunun araştırılması., 2023.
  6. Kronik miyeloid lösemi hücrelerinde koku reseptörü OR2AT4’ün apoptotik sinyal yolaklarına etkisinin α-Bisabolol maddesi ile modülasyonunun araştırılması., 2023.
  7. Filogenetik Olarak GSK-3β Molekülünde Korunan Bölgelerin Nörodejenerasyondaki Etkisinin Araştırılması, 2023.
  8. Alzheimer Hastalarında Plazmadan Gen Anlatım Analizi, 2023.
  9. Kuersetin-Saponin Molekülleri ile Kronik Myeloid Lösemi Hücrelerinde Antikanser Etkisinin Araştırılması ve Sinyal Yolaklarının Belirlenmesi, 2021.
  10. İn vitro ateroskleroz modellemesinde Vaccinium myrtillus I. ekstresinin atero koruyucu etkisinin araştırılması, 2022.
  11. İn vitro Parkinson modelinde Hypericum perforatum ekstresinin nöro-koruyucu etkisinin moleküler mekanizmalarının araştırılması, 2022.
  12. Aluminyum Maltolat ile oluşturulan Alzheimer modelinde Hypericum perforatum ekstresinin antioksidan etkisinin araştırılması, 2022.
  13. İn vitro kan beyin bariyerinde gallik asitin demir nörotoksisistesine bağlı antioksidan etkisinin araştırılması, 2021.
  14. FOLİK ASİTİN İNSAN NÖROBLASTOMA (SH-SY5Y) HÜCRELERİNDE OLUŞAN OKSİDATİF STRESE KARŞI ETKİSİNİN ARAŞTIRILMASI, 2018.
  15. Ceratonia siliqua EKSTRESİNİN, ANDROJEN RESEPTÖRÜ (NR3C4) GEN DÜZENLENME MEKANİZMALARI ÜZERİNE ETKİSİNİN ARAŞTIRILMASI, 2018.
  16. Östrojenin Nöroinflamasyon üzerine etkisinin araştırılması, 2018.
  17. Nörodejeneratif Hastalıkların Moleküler Temellerinin Araştırılması, 2019.
  18. Chlorophyceae, Cyanophyceae, Prymnesiophyceae, Eustigmatophyceae ve Bacillariophyceae Ailesine Ait Mikroalglerin Antilösemik İlaç Potansiyellerinin Moleküler ve Mekanistik Temellerinin Araştırılması, 2016.

Akademik Faaliyetler > Kongre - Konferans Katılım

  1. 11th International Artemis Scientific Research Congress, 2025.
  2. 11. Uluslararası “Artemis” Bilimsel Araştırmalar Kongresi, 2025.
  3. Basic Clinical and Multimodal Imaging (BaCI), 2023.
  4. 10th International Multidisciplinary Conference on Economics, Business, Technology and Social Sciences, 2022.
  5. 2. Multidisipliner Nörodejenerasyon Kongresi, 2020.
  6. 2nd ICSTR Rome – International Conference on Science & Technology Research, 2019.
  7. 2nd ICSTR Rome – International Conference on Science & Technology Research, 2019.
  8. Alzheimer Sempozyumu, 2019.
  9. 6th International Congress of the Molecular Biology Association of Turkey, 2018.

İdari Faaliyetler

  1. Öğrenci Danışmanlığı / Student Adviser, 100 -150 Öğrenci Danışmanlığı, (2024 - 2025)
  2. Kurul Üyeliği / Board Member, Uygulama ve Araştırma Merkezi, (2021 - 2022)
  3. Kurul Üyeliği / Board Member, Diğer Fakültelerde Kurul Üyeliği, (2020 - Devam ediyor.)
  4. Bölüm Başkanlığı / Head of Department, Moleküler Biyoloji ve Genetik (Türkçe), (2019 - Devam ediyor.)
  5. Kurul Üyeliği / Board Member, Fakülte Kurulu Üyeliği, (2018 - Devam ediyor.)
  6. Komisyon Başkanlığı / Head of Commission, Eğitim Komisyonu (Enstitü / Fakülte / MYO), (2019 - 2022)
  7. Koordinatör / Coordinator, Erasmus Bölüm Koordinatörlüğü, (2018 - 2020)
  8. Komisyon Üyesi / Member of Commission, Uluslararası Öğrenciler Akademik Komisyonu, (2019 - 2024)
  9. Komisyon Üyesi / Member of Commission, Etkinlik Komisyonu, (2019 - 2022)
  10. Koordinatör / Coordinator, Bologna Bölüm Koordinatörlüğü, (2019 - Devam ediyor.)
  11. Çalışma Grubu Üyelikleri / Research Group Membership, Nörogörüntüleme Çalışma Grubu, (2019 - Devam ediyor.)
  12. Kurul Üyeliği / Board Member, Fakülte Yönetim Kurulu Üyeliği, (2018 - 2023)
  13. Komisyon Üyesi / Member of Commission, Eğitim Komisyonu (Enstitü / Fakülte / MYO), (2018 - 2022)
  14. Çalışma Grubu Üyelikleri / Research Group Membership, Moleküler Biyoteknoloji Çalışma Grubu, (2018 - 2023)
  15. Laboratuvar, Laboratuvar Sorumlusu, (2016 - Devam ediyor.)
  16. Laboratuvar, Laboratuvar Yöneticisi, (2013 - Devam ediyor.)

Bilimsel Üyelikler

  1. Türk Fizyolojik Bilimler Derneği Üyeliği 2019
  2. Türk Fizyolojik Bilimler Derneği Üyeliği 2021
  3. ARGEYEP-Danışma Kurulu Üyeliği 2022

Eğitim ve Öğretim Faaliyetleri

  1. Üniversite Kültürü II, (Lisans / 2023-2024 Bahar)
  2. Medical Committee Courses (Com 2B), (Lisans / 2023-2024 Bahar)
  3. Mezuniyet Tezi, (Lisans / 2023-2024 Bahar)
  4. Fizyoloji, (Lisans / 2023-2024 Bahar)
  5. Medical Committee Courses (Com 2A), (Lisans / 2023-2024 Güz)
  6. Proje, (Lisans / 2023-2024 Güz)
  7. İmmunoloji, (Lisans / 2023-2024 Güz)
  8. Sinyal Transdüksiyon, (Lisans / 2023-2024 Güz)
  9. Graduation Project, (Lisans / 2023-2024 Güz)
  10. Biyolojik Saat, (Lisans / 2023-2024 Güz)