Belkıs ATASEVER ARSLAN, Ph.D

Professor

belkis.arslanuskudar.edu.tr

(0216) 400 22 22 / 2602

ORCID: 0000-0001-5827-8484

Documents : 36 | Citation : 503 | h-index : 13

Citation : 765 | h-index : 15 | i10-index : 19

: 80
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Research Fields

Physiology, Immunology, Signal Transduction

UN Sustainable Development Goal Labels Matching with Research Fields

3

Short CV

Assoc.Prof. Belkıs Atasever Arslan was born in 1980 in Istanbul. In 2001, he graduated from Istanbul University, Department of Biology. She received his master's degree in 2004 and doctorate degree in 2008 in the Department of Physiology at Istanbul University, Istanbul Medical Faculty.
In 2009, she was one of three researchers winning researcher postdoctoral fellowship in Turkish Academy of Sciences. In the same year, she also received a postdoctoral scholarship from TUBITAK and had worked as post doc in Sabancı University, Department of Biological Sciences and Bioengineering for 3 years.
She started to work as an assistant professor at Üsküdar University in 2012. In 2018, she received the title of Associate Professor in the field of Medical Physiology. In 2019, she was appointed as Adjunct Associate Professor to the Department of Anatomy and Cell Biology, School of Medicine, University of Illinois at Chicago. Assoc.Prof. Belkıs Atasever Arslan has 2 European patent registrations and several patent applications. She works on drug discovery, immunology and signal transduction.
She is married and has two children.

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Education Status & Academic Titles

2001

Undergraduate Degree

İstanbul Üniversitesi Biyoloji

2004

Master Degree

İstanbul Üniversitesi, İstanbul Tıp Fakültesi Fizyoloji

2008

Doctorate

İstanbul Üniversitesi, İstanbul Tıp Fakültesi Fizyoloji

Associate Professorship

Üsküdar Üniversitesi Sağlık Bilimleri-Fizyoloji

2018

Professorship

Üsküdar Üniversitesi Fizyoloji

2023

Supervised Graduate Theses

  1. Sesamolün Kan-Beyin Bariyerinde Sigara Dumanı Toksisitesine Karşı Koruyucu Etkilerinin Araştırılması, 2024.
  2. ARPE-19 hücrelerinde yüksek glikoza karşı FPS-ZM1 ve trans-anetolün yara iyileşme üzerine etkisi, 2024.
  3. Kuarsetin, Berberin, Saponin ve Krisin Moleküllerinin Akciğer Kanser Hücrelerinde Antikanser Etkisinin Araştırılması ve Etkilediği Sinyal Yolaklarının Belirlenmesi, 2020.
  4. Alzheimer hastalığında PSMD9 gen polimorfizmi, 2019.
  5. Otistik Spektrum Bozukluğunun Genetik Altyapısının ve Moleküler Sinyal Yolakların Araştırılması., 2016.

Academic Activities > Publications

(Scopus) Toplam: 41

A square planar cobalt(II)-thiosemicarbazone complex. Synthesis, characterization, antiviral and anti-inflammatory potential

Journal of Molecular Structure (2024)

Effect of Iron Overload on Tight Junctions and Adhesion Molecules in ECV304 Cells

Toxicology International (2024)

Gene expression analysis in plasma of patients with Alzheimer's disease

Neuroscience Research Notes (2024)

Effects of Vaccinium myrtillus L. Extract on TNF-α-induced Inflammation through Human Paraoxonases

Roumanian Journal of Chemistry (2023)

Selective cytotoxicity of chemical composition of Spirulina platensis extract in endometrial cells: In vitro and in silico approach

Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi (2023)

Synthesis, SARS‐CoV‐2 3CL main protease inhibitor, anti‐inflammatory and wound healing effects of a zinc(II)‐thiosemicarbazone complex

Applied Organometallic Chemistry (2023)

Effects of Hypericum perforatum extract on 6-OHDA neurotoxicity in differentiated SH-SY5Y cells

Egyptian Pharmaceutical Journal (2023)

Chemical Constituent of Isochrysis galbana Microalgae Extract And Its Cytotoxic Activities On Leukemic Cell Lines

İstanbul Journal of Pharmacy (2022)

Differential CTCF binding in motor neurons and lymphocytes

F1000Research (2021)

The iron(III) and nickel(II) complexes with tetradentate thiosemicarbazones. Synthesis, experimental, theoretical characterization, and antiviral effect against SARS-Cov2

Journal of Molecular Structure (2021)

Tumor necrosis factor alpha gene rs1799724 polymorphism in Alzheimer’s disease

General physiology and biophysics (2020)

Immunotherapy Approaches on Innate Immunity for SARS-Cov2

Acta virologica (2020)

Bioelectricity generation using human neuronal-like cells in single chamber biofuel cells

Journal of Cleaner Production (2020)

Proteasome modulator 9 (PSMD9) gene rs14259 polymorphism in Alzheimer’s disease

Bratislava Medical Journal (2020)

Proteasome modulator 9 gene rs14259 polymorphism in patients with diabetic polyneuropahy

Archives of Neuropsychiatry (2019)

Rabies Virus 31D Peptide‐[P(VP‐co‐AA)] Conjugates: Synthesis, Characterization and Cytotoxicity Evaluation

CHEMISTRYSELECT (2019)

Synergistic effects of quercetin and selenium on oxidative stress in endometrial adenocarcinoma cells

Bratislava Medical Journal (2019)

Synergistic effects of quercetin and selenium on oxidative stress in endometrial adenocarcinoma cells.

Bratislava Medical Journal (2019)

Resin extract obtained from Cilician fir (Abies Cilicica) inhibits glucose dependent inflammation in vitro

journal of experimental therapeutics and oncology (2019)

Androgen Receptor (NR3C4) regulator potential of Ceratonia siliqua extract and its signaling pathways

PHARMACOGNOSY MAGAZINE (2018)

Chemical and molecular characterization of metabolites from Flavobacterium sp.

PLOS ONE (2018)

Apoptotic effect of Nigella sativa on human lymphoma U937 cells

Pharmacognosy Magazine (2017)

Dinutuximab in the Treatment of High-Risk Neuroblastoma in Children

CLINICAL MEDICINE INSIGHTS-THERAPEUTICS (2017)

Apoptotic mechanisms of nickel(II) complex with N1-acetylacetone-N4-4-methoxy-salicylidene-S-allyl-thiosemicarbazone on HL60 leukemia cells

GENERAL PHYSIOLOGY AND BIOPHYSICS (2016)

Potential of GRID2 receptor gene for preventing TNF-induced neurodegeneration in autism

NEUROSCIENCE LETTERS (2016)

High Plasma Pentraxin 3 Levels in Diabetic Polyneuropathy Patients with Nociceptive Pain.

The Tohoku Journal of Experimental Medicine (2016)

Screening of new antileukemic agents from essential oils of algae extracts and computational modeling of their interactions with intracellular signaling nodes

European Journal of Pharmaceutical Sciences (2016)

The effect of saffron (its active constituent, crocin) on the cardiovascular complication and dyslipidemia in streptozotocin induced diabetic rats

African Journal of Traditional, Complementary and Alternative Medicines (2015)

Cytotoxic effect of extract from Dunaliella salina against SH-SY5Y neuroblastoma cells

GENERAL PHYSIOLOGY AND BIOPHYSICS (2015)

Recently Emerging Signaling Landscape of Ataxia-Telangiectasia Mutated (ATM) Kinase

Asian Pacific Journal of Cancer Prevention (2014)

Effects of Micro Environmental Factors on Natural Killer Activity NK of Beta Thalassemia Major Patients

Cellular Immunology (2013)

CD8 lineage-specific regulation of interleukin-7 receptor expression by the transcriptional repressor Gfi1

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Decreased IFN-γ and IL-12 levels in panic disorder

Journal of Psychosomatic Research (2012)

Chemical constituents of the different parts ofColchicum baytopiorumand their cytotoxic activities on K562 and HL60 cell lines

Pharmaceutical Biology (2009)

Cytotoxic activities of new iron(III) and nickel(II) chelates of some S-methyl-thiosemicarbazones on K562 and ECV304 cells

Investigational New Drugs (2009)

Synthesis, Characterization and Cytotoxic Properties of Pd(II), Cd(II) and Hg(II) Complexes of 2-Amino-5-Chloro-Benzophenone-4-(H/Ph)-Thiosemicarbazones

Main Group Metal Chemistry (2008)

Synthesis, characterisation and cytotoxic properties of the N1,N4-diarylidene-S-methyl-thiosemicarbazone chelates with Fe(III) and Ni(II)

European Journal of Medicinal Chemistry (2006)

Cytotoxic effects of leaf, stem and root extracts of Nerium oleander on leukemia cell lines and role of the p-glycoprotein in this effect

Journal of Experimental Therapeutics and Oncology (2006)

IN VITRO EFFECTS OF VITAMIN C AND SELENIUM ON NK ACTIVITY OF PATIENTS WITH β -THALASSEMIA MAJOR

Pediatric Hematology and Oncology (2005)

Normal and leukemic hematopoiesis

Sendrom (2004)

Effects of flavonoids obtained from Cynara syriaca on leukemic cells

Ankara Universitesi Eczacilik Fakultesi Dergisi (2003)

Academic Activities > Publications

(Other Scientific Publications) Toplam: 18

IN VITRO ANTILEUKEMIC ACTIVITY OF EUPHORBIA ECHINUS EXTRACT

Biotechnologia Acta (2023)

PHYTOCHEMICAL CONSTITUENTS AND ANTILEUKEMIC EFFECTS OF JUNIPERUS OXYCEDRUS EXTRACT

Biotechnologia Acta (2022)

Neuroprotective effect of Hypericum perforatum extract against Aluminum-maltolate induced toxicity in SH-SY5Y cells

International Journal of Science Letters (2022)

Beyin Homeostazında Bakır, Demir, Çinko Elementlerinin Parkinson Hastalığı ile İlişkisi

Doğu Fen Bilimleri Dergisi (2022)

The Role of Iron, Copper and Zinc Elements in the Pathogenesis of Alzheimer's Disease

Anatolian Journal of Biology (2022)

NK Hücre Aktivitesinde İmmunomodulatör Etki Gösteren Moleküller

Black Sea Journal of Health Science (2022)

Anti-diabetic Effects of Berberis cretica Extract in INS-1E Cells

International Journal of Science Letters (2021)

Conserved amino acids in HCoV-HKU1 and SARS-Cov2 at RNA-dependent RNA polymerase (RdRp) motifs

Anatolian Journal of Biology (2021)

Protective Effects of Folic Acid and Vitamin C Against Iron Overload at the in vitro Blood-Brain Barrier

International Journal of Life Sciences and Biotechnology (2021)

Does Radiotherapy Augment Natural Killer Cell Function in Pediatric Acute Lymphoblastic Leukemia?

Istanbul University Institute of Health Sciences Journal of Advanced Research in Health Sciences (2021)

AXONAL TRANSPORT OF ALPHA SYNUCLEIN FIBRILS IN PARKINSON’S DISEASE

Journal of Neurobehavioral Sciences (2019)

Possible microRNAs participating in Alzheimers pathology via signaling pathways affecting axonal transport.

journal of neurobehavioral sciences (2019)

Impact of SCN1A gene mutations on hippocampal NaV1.1 sodium channels in Dravet Syndrome

JNBS (2019)

EFFECTS OF ESTROGEN ON KYNURENINE PATHWAY AND NF-kB IN TNF-α INDUCED NEUROINFLAMMATION.

JNBS (2018)

Cytotoxicity, Total Phenolic and Flavonoid Contents of Momordica charantıa in Neuroblastoma Cells.

J Neurobehav Sci (2018)

Therapeutic Effects of Probiotics on Multiple Sclerosis (MS) Diseases vıa TH17 Cells.

J Neurobehav Sci (2018)

Axonal Transport in Neurodegenerative Diseases.

J Neurobehav Sci (2018)

Natural Killer (NK) Cells in β Thalassemia Major Patients

JSM Biotechnol Bioeng (2014)

Academic Activities > Book - Book Chapter

(Other) Toplam: 3
  1. Bölüm : Hücre altı düzeyde akson ve dendrit tipleri, fonksiyonel özellikleri (Fonksiyonun Cerrahi Anatomisi), Pınar Öz, Belkıs Atasever Arslan, , US Akademi, 2019
  2. Nöron ve nöroglianın tipleri, histopatolojik özellikleri (Fonksiyonun Cerrahi Anatomisi), Belkıs Atasever Arslan, , Intertıp Yayınevi, 2018
  3. Hücre altı düzeyde protein sentezi, hücre iskeleti oluşumu ve fonksiyonel özellikleri (Fonksiyonun Cerrahi Anatomisi), Belkıs Atasever Arslan, Kaan YilancioĞlu, , Intertıp Yayınevi, 2018

Academic Activities > Editörlük

  1. Turkish Journal of Biology, ISBN:1300-0152, 2022.

Projects > Projects

  1. Sesamolün Kan-Beyin Bariyerinde Sigara Dumanı Toksisitesine Karşı Koruyucu Etkisinin Araştırılması, 2025.
  2. Bakır (Iı) Ve Ph Kombinasyonunun, Amiloid R (AR) Plak Oluşumunda "Self Assembly" Mekanizmalarına Etkisinin Araştırılması., 2024.
  3. Tetradentat tiyosemikarbazon ligandı taşıyan kobalt (II) ve çinko (II) komplekslerinin antiviral ve antiinflamatuvar etkilerinin araştırılması, 2024.
  4. Betainin Kronik Myeloid Lösemi Hücrelerinde Antikanser Etkisinin Araştırılması ve Sinyal Yolaklarının Belirlenmesi., 2023.
  5. Sigara dumanı ekstresinin endotel hücrelerinde adezyon molekülleri ve sinyal yolakları üzerine etkisinin sesamol ile modülasyonunun araştırılması., 2023.
  6. Kronik miyeloid lösemi hücrelerinde koku reseptörü OR2AT4’ün apoptotik sinyal yolaklarına etkisinin α-Bisabolol maddesi ile modülasyonunun araştırılması., 2023.
  7. Filogenetik Olarak GSK-3β Molekülünde Korunan Bölgelerin Nörodejenerasyondaki Etkisinin Araştırılması, 2023.
  8. Alzheimer Hastalarında Plazmadan Gen Anlatım Analizi, 2023.
  9. Kuersetin-Saponin Molekülleri ile Kronik Myeloid Lösemi Hücrelerinde Antikanser Etkisinin Araştırılması ve Sinyal Yolaklarının Belirlenmesi, 2021.
  10. İn vitro ateroskleroz modellemesinde Vaccinium myrtillus I. ekstresinin atero koruyucu etkisinin araştırılması, 2022.
  11. İn vitro Parkinson modelinde Hypericum perforatum ekstresinin nöro-koruyucu etkisinin moleküler mekanizmalarının araştırılması, 2022.
  12. Aluminyum Maltolat ile oluşturulan Alzheimer modelinde Hypericum perforatum ekstresinin antioksidan etkisinin araştırılması, 2022.
  13. İn vitro kan beyin bariyerinde gallik asitin demir nörotoksisistesine bağlı antioksidan etkisinin araştırılması, 2021.
  14. FOLİK ASİTİN İNSAN NÖROBLASTOMA (SH-SY5Y) HÜCRELERİNDE OLUŞAN OKSİDATİF STRESE KARŞI ETKİSİNİN ARAŞTIRILMASI, 2018.
  15. Ceratonia siliqua EKSTRESİNİN, ANDROJEN RESEPTÖRÜ (NR3C4) GEN DÜZENLENME MEKANİZMALARI ÜZERİNE ETKİSİNİN ARAŞTIRILMASI, 2018.
  16. Östrojenin Nöroinflamasyon üzerine etkisinin araştırılması, 2018.
  17. Nörodejeneratif Hastalıkların Moleküler Temellerinin Araştırılması, 2019.
  18. Chlorophyceae, Cyanophyceae, Prymnesiophyceae, Eustigmatophyceae ve Bacillariophyceae Ailesine Ait Mikroalglerin Antilösemik İlaç Potansiyellerinin Moleküler ve Mekanistik Temellerinin Araştırılması, 2016.

Academic Activities > Congress - Conference Participation

  1. Basic Clinical and Multimodal Imaging (BaCI), 2023.
  2. 10th International Multidisciplinary Conference on Economics, Business, Technology and Social Sciences, 2022.
  3. 2. Multidisipliner Nörodejenerasyon Kongresi, 2020.
  4. 2nd ICSTR Rome – International Conference on Science & Technology Research, 2019.
  5. 2nd ICSTR Rome – International Conference on Science & Technology Research, 2019.
  6. Alzheimer Sempozyumu, 2019.
  7. 6th International Congress of the Molecular Biology Association of Turkey, 2018.

Administrative Activities

  1. Öğrenci Danışmanlığı / Student Adviser, 100 -150 Öğrenci Danışmanlığı, (2024 - Devam ediyor.)
  2. Kurul Üyeliği / Board Member, Uygulama ve Araştırma Merkezi, (2021 - 2022)
  3. Kurul Üyeliği / Board Member, Diğer Fakültelerde Kurul Üyeliği, (2020 - Devam ediyor.)
  4. Bölüm Başkanlığı / Head of Department, Moleküler Biyoloji ve Genetik (Türkçe), (2019 - Devam ediyor.)
  5. Kurul Üyeliği / Board Member, Fakülte Kurulu Üyeliği, (2018 - Devam ediyor.)
  6. Komisyon Başkanlığı / Head of Commission, Eğitim Komisyonu (Enstitü / Fakülte / MYO), (2019 - 2022)
  7. Koordinatör / Coordinator, Erasmus Bölüm Koordinatörlüğü, (2018 - 2020)
  8. Komisyon Üyesi / Member of Commission, Uluslararası Öğrenciler Akademik Komisyonu, (2019 - 2024)
  9. Komisyon Üyesi / Member of Commission, Etkinlik Komisyonu, (2019 - 2022)
  10. Koordinatör / Coordinator, Bologna Bölüm Koordinatörlüğü, (2019 - Devam ediyor.)
  11. Çalışma Grubu Üyelikleri / Research Group Membership, Nörogörüntüleme Çalışma Grubu, (2019 - Devam ediyor.)
  12. Kurul Üyeliği / Board Member, Fakülte Yönetim Kurulu Üyeliği, (2018 - 2023)
  13. Komisyon Üyesi / Member of Commission, Eğitim Komisyonu (Enstitü / Fakülte / MYO), (2018 - 2022)
  14. Çalışma Grubu Üyelikleri / Research Group Membership, Moleküler Biyoteknoloji Çalışma Grubu, (2018 - 2023)
  15. Laboratuvar, Laboratuvar Sorumlusu, (2016 - Devam ediyor.)
  16. Laboratuvar, Laboratuvar Yöneticisi, (2013 - Devam ediyor.)

Scientific Memberships

  1. ARGEYEP-Danışma Kurulu Üyeliği 2022
  2. Türk Fizyolojik Bilimler Derneği Üyeliği 2021
  3. Türk Fizyolojik Bilimler Derneği Üyeliği 2019

Education and Training Activities