TÜBİTAK success from our Faculty of Medicine student...
Üsküdar University students and faculty members continue to achieve significant success. İlayda Güvel, who is a 2nd year student from the Department of English at the Faculty of Medicine, was entitled to be supported as a scholar with her project titled "Cholesterol-induced in vitro lipid accumulation and the effect of NRF-2 activation in in vivo NASH models" within the scope of TÜBİTAK-STAR Undergraduate scholarship program. The coordinator of the project is Prof. Nesrin Kartal Özer, who is a faculty member of the Faculty of Medicine, and the researcher was Asst. Prof. Tuğçe Demirel Yalçıner. Also, İlayda Güvel, who started working on the project, continues her research.
İlayda Güvel, who is a 2nd year student of the English program of the Faculty of Medicine, was entitled to be supported as a scholar within the scope of the TÜBİTAK-STAR Undergraduate scholarship program in the TÜBİTAK-COST project numbered 223S770 project, and Güvel started to work in the project.
The coordinator of the project is Faculty of Medicine Prof. Nesrin Kartal Özer and researcher was Asst. Prof. Tuğçe Demirel Yalçıner.
"We hope to contribute to the development of new treatment strategies"
Talking about the aims of the project, Department of English at the Faculty of Medicine 2nd year student İlayda Güvel stated that "The discovery of new ways to alleviate liver damage caused by cholesterol is our main goal. We aim to investigate the role of the transcription factor Nrf-2 in alleviating cholesterol-induced lipid accumulation and Nonalcoholic Steatohepatitis (NASH). By improving our understanding of these processes, we hope to contribute to the development of new treatment strategies with broad implications for other chronic conditions such as liver diseases due to dysregulated lipid metabolism, cardiovascular diseases, and metabolic syndrome."
"Our biggest goal is to offer new perspectives on potential treatments"
Underlining that their biggest goal is to offer new perspectives on potential treatments with the research, Güvel stated that "The main reason we undertook the project was that there was a critical need to understand the increasing prevalence of nonalcoholic steatohepatitis (NASH) and other liver diseases caused by cholesterol, i.e. linked to lipid accumulation. NASH, a severe form of nonalcoholic fatty liver disease (NAFLD), can lead to liver inflammation, cirrhosis, and liver failure. Unfortunately, there are currently limited opportunities for effective treatment options. With this research, our biggest goal is to reveal new mechanisms and pathways that cause the progression of liver diseases and to offer new perspectives on potential treatments. With this research, we hope to uncover new mechanisms and pathways that cause the progression of liver diseases, to offer new perspectives on potential treatments, and to benefit patients suffering from this challenging condition in the light of my esteemed professors."
"I want to contribute to the development of personalized medicine approaches"
Talking about her future goals, Güvel stated that being involved in this project inspired her to specialize in the field of internal medicine. Güvel expressed that "I plan to continue to explore my new interests based on the knowledge I have gained from conducting research throughout my medical education. I am committed to continuing my research into the molecular mechanisms underlying chronic diseases with a focus on oxidative stress and lipid metabolism. In this way, I would like to contribute to the development of personalized medicine approaches that tailor treatments to individual patients. Being involved in this project inspired me to specialize in internal medicine after medical school. I want to integrate the research knowledge I have gained into clinical practice, focusing on diagnosing and managing complex conditions."
Üsküdar News Agency (ÜNA)