Nesrin KARTAL ÖZER, Ph.D

Nesrin KARTAL ÖZER, Ph.D

ORCID0000-0002-4968-3178

Prof.

Faculty of Medicine / Department of Medical Biochemistry / Metabolic and Inflammatory Diseases Application and Research Center - Director

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Academic Connections

Scopus
Documents:85
Citations:3521
h-index:30
Google Scholar
Citations:5581
h-index:36
i10-index:68

190

Web of ScienceResearchgateYÖKPublons

Research Areas

Endoplazmik retikulum stress
Lipit birikimi
Yüksek yağlı diyet
Yağlı karaciğer hastalığı
Metabolik hastalıklar

Short CV

Nesrin Kartal Ozer, is Professor at Uskudar University, Faculty of Medicine, Department of Biochemistry, Istanbul,Turkey. She graduated with a BSc in Pharmacy from Hacettepe University, Ankara, Turkey and she has received her PhD in Biochemistry in Hacettepe University, Faculty of Medicine. She moved then to Marmara University, Istanbul and worked there until 2022. She was a Visiting Scientist at St.George’s Hospital, Medical School, Department of Biochemistry, London, UK (1985-1986); Institute of Biochemistry and Molecular Biology, University of Bern, Switzerland (1993-2004) and University of Hohenheim, Stuttgart, Germany (2008). In her research she published more than 100 articles and she was invited speaker at ~80 international meetings. She was the organizer ~10 scientific meetings and conferences. As member of International Organizations, it is worth mentioning her membership in the International Advisory Committee, Oxygen Club of California (1999- today); FEBS Advanced Course Committee Member (2003-2006); FEBS Fellowships Committee Member (2021-2024), Secretary General Society for Free Radical Research-Europe (SFRR-E) and Member of the Council (2003-2009) and President of SFRR-E (2013-2014). She was awarded The Oxygen Club of California Award and “Life Time Honorary Member” in 2006 “In recognition of outstanding research contributions on the role of vitamin E in atherosclerosis and to fostering the field of free radical biology” and The Society for Free Radical Research-Europe Lifetime Achievement Award in 2019 “In recognition of Lifetime Extraordinary Scientific Achievements in the Field of Free Radical Research”. Her research focus on endoplasmic reticulum stress, redox signaling and cell death in metabolism related diseases such as cardiovascular diseases and non-alcoholic fatty liver disease. In parallel she has carried out research on the molecular function of tocopherols in these diseases.

Education & Academic Titles

Bachelor's Degree

Hacettepe Üniversitesi

1977

Master's Degree

Hacettepe Üniversitesi

1980

Doctorate

Hacettepe Üniversitesi, Tıp Fakültesi

1983

Assistant Professor

Marmara Üniversitesi, Tıp Fakültesi

1987

Associate Professor

Marmara Üniversitesi, Tıp Fakültesi

1988

Professor

Marmara Üniversitesi, Tıp Fakültesi

1994

Projects > Projects

Total: 14

1

Uzun zincirli vitamin E metaboliti garsinoik asit etkinliğinin farelerde oluşturulacak yağlı karaciğer modelinde değerlendirilmesi
2027

2

Uzun zincirli vitamin E metaboliti garsinoik asit etkinliğinin farelerde oluşturulacak yağlı karaciğer modelinde değerlendirilmesi
2027

3

Uzun zincirli vitamin E metaboliti garsinoik asit etkinliğinin farelerde oluşturulacak yağlı karaciğer modelinde değerlendirilmesi
2028

4

: Uzun zincirli vitamin E metaboliti garsinoik asit etkinliğinin farelerde oluşturulacak yağlı karaciğer modelinde değerlendirilmesi
2028

5

Alfa-13-COOH yüklü makrofaj hedefli nanopartikül etkinliğinin yağlı karaciğer hastalığında incelenmesi
2027

6

Alfa-13-COOH Yüklü Makrofaj Hedefli Nanopartikül Etkinliğinin Yağlı Karaciğer Hastalığında Incelenmesi”
2027

7

Yüksek kolesterol içeriğine sahip fruktoz palmitat ve trans-yağ diyeti ile indüklenen Non-Alkolik Yağlı Karaciğer hastalığından Steatohepatite geçişte ferroptozisin rolünün in vivo olarak incelenmesi
2025

8

SREBP1c inhibisyonunun fruktoz ile indüklenen lipit birikimine etkisinin hepatositlerde belirlenmesi
2025

9

SREBP1c İinhibisyonunun fruktoz ile indüklenen lipit birikimine etkisinin hepatositlerde belirlenmesi
2025

10

Kolesterol ile indüklenen in vitro lipit birikimi ve in vivo NASH modellerinde NRF-2 aktivasyonunun etkisi
2026

11

Kolesterol ile İndüklenen İn vitro lipit birikimi ve in vivo NASH modellerinde Nrf-2 aktivasyonunun etkisi
2026

12

Garsinoik Asit ve 17-oxo-DHA'nın Inflamasyona Karşı Etkinliğinin In Vitro ve In Vivo Modeller Kullanılarak Değerlendirilmesi
2024

13

Seipin Proteinin Yüksek Kolesterollü Diyet ile Indüklenen Yağlı Karaciğer Hastalığındaki Rolünün Saptanması
2024

14

Seipin Proteinin Yüksek Kolesterollü Diyet ile İndüklenen Yağlı Karaciğer Hastalığındaki Rolünün Saptanması
2024

Supervised Graduate Theses

Total: 1

1

Lipit Birikiminde Rol Alan Seipin Proteinin Kolesterol İle İndüklenen Yağlı Karaciğer Modelinde Endoplazmik Retikulum Stres ve Otofaji Üzerine Etkisi
2023

Academic Activities > Editorship

Total: 6

ISSN: The ISSN of Metabolism: Clinical and Experimental journal is 00260495, 15328600.,
2015
ISSN: ISSN: 23523646,
2015
ISSN: ISSN 1521-6551,
2020
ISSN: 2211-5463,
2024
ISSN: 1521-6551,
2024
ISSN: 2211-5463,
2024

Academic Activities > Congress - Conference Participation

Total: 13

1

Gen tedavisinde yeni bir yaklaşım: Hedef hücre spesifik siRNA uygulamaları
2025

2

Hepatocyte seipin silencing reduces cholesterol mediated lipid droplet maturation in fatty liver model.
2024

3

HEPATIC SEIPIN DEFICIENCY REDUCES CHOLESTEROL MEDIATED LIPID DROPLET MATURATION DEPENDENT OF ENDOPLASMIC RETICULUM STRESS BUT NOT LIPOPHAGY.
2024

4

Role Of Nrf2 In Protective Effects Of The Electrophilic Metabolite Of Docosahexaenoic Acid Against Uvb-Induced Oxidative Cell Death And Inflammation In Mouse Skin
2024

5

Investigating Garcinoic Acid-Regulated Anti-Inflammatory Effect On Bone-Marrow Derived Macrophages
2024

6

Nanoparticle-Mediated Delivery of α-13’-COOH to Macrophages:Assessing in vitro Potential
2024

7

Garcinoic Acid Alleviates Cholesterol Mediated Lipid Accumulation in Hepatocytes: Role of NRF2/HO-1 Pathway.
2024

8

Role Of SREBP1c And Lipophagy In Fructose Mediated Lipid Accumulation In Hepatocytes.
2024

9

Molecular mechanism of lipid accumulation in non-alcoholic fatty liver disease: new targets for the clinic
2023

10

Cholesterol impact on cellular stress promoting nonalcoholic steatohepatitis
2022

11

Alpha-tocopherol supplementation in cholesterol fed rabbits demonstrated anti-inflammatory and anti-apoptotic properties reducing NASH progression
2022

12

An electrophilic metabolite of docosahexaenoic acid protects against UVB-induced dermatitis
2022

13

High Cholesterol Induced Endoplasmic Reticulum Stress Signaling: Role in the Progression of Cardiovascular Diseases
2022

Administrative Activities

Total: 4

1

METİFLAM
2024

2

FİHADEK
2024

3

Nörogenetik Çalışma Grubu
2023

4

ARGEYEP Yürütme Kurulu Üyeliği
2022

Education and Teaching Activities

Total: 6

1

Medical Committee Courses (Com 2B)
LISANS / 2024

2

Medical Committee Courses (Committee 1B)
LISANS / 2024

3

Medical Committee Courses (Committee 3B)
LISANS / 2024

4

Kanserin Moleküler Temelleri ve Hücresel Sinyal İletim Yolakları
DOKTORA / 2024

5

Medical Committee Courses (Committee 3A)
LISANS / 2024

6

Medical Committee Courses (Com 1A)
LISANS / 2024