Nesrin KARTAL ÖZER, Ph.D

Professor

nesrin.kartalozeruskudar.edu.tr

(0216) 400 2222 / 3242

ORCID: 0000-0002-4968-3178

Documents : 79 | Citation : 3252 | h-index : 29

Citation : 5230 | h-index : 36 | i10-index : 63

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Research Fields

Endoplasmic reticulum stress, Lipid accumulation, High fat diet, Fatty liver disease, Metabolic diseases

UN Sustainable Development Goal Labels Matching with Research Fields

3

Short CV

Nesrin Kartal Ozer, is Professor at Uskudar University, Faculty of Medicine, Department of Biochemistry, Istanbul,Turkey. She graduated with a BSc in Pharmacy from Hacettepe University, Ankara, Turkey and she has received her PhD in Biochemistry in Hacettepe University, Faculty of Medicine. She moved then to Marmara University, Istanbul and worked there until 2022. She was a Visiting Scientist at St.George’s Hospital, Medical School, Department of Biochemistry, London, UK (1985-1986); Institute of Biochemistry and Molecular Biology, University of Bern, Switzerland (1993-2004) and University of Hohenheim, Stuttgart, Germany (2008). In her research she published more than 100 articles and she was invited speaker at ~80 international meetings. She was the organizer ~10 scientific meetings and conferences. As member of International Organizations, it is worth mentioning her membership in the International Advisory Committee, Oxygen Club of California (1999- today); FEBS Advanced Course Committee Member (2003-2006); FEBS Fellowships Committee Member (2021-2024), Secretary General Society for Free Radical Research-Europe (SFRR-E) and Member of the Council (2003-2009) and President of SFRR-E (2013-2014). She was awarded The Oxygen Club of California Award and “Life Time Honorary Member” in 2006 “In recognition of outstanding research contributions on the role of vitamin E in atherosclerosis and to fostering the field of free radical biology” and The Society for Free Radical Research-Europe Lifetime Achievement Award in 2019 “In recognition of Lifetime Extraordinary Scientific Achievements in the Field of Free Radical Research”. Her research focus on endoplasmic reticulum stress, redox signaling and cell death in metabolism related diseases such as cardiovascular diseases and non-alcoholic fatty liver disease. In parallel she has carried out research on the molecular function of tocopherols in these diseases.

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Education Status & Academic Titles

1977

Undergraduate Degree

Hacettepe Üniversitesi Eczacılık Fakültesi

1980

Master Degree

Hacettepe Üniversitesi Klinik Analiz

1983

Doctorate

Hacettepe Üniversitesi, Tıp Fakültesi Biyokimya (TIP)


Associate Professorship

Marmara Üniversitesi, Tıp Fakültesi Biyokimya

1988

Professorship

Marmara Üniversitesi, Tıp Fakültesi Biyokimya

1994

Supervised Graduate Theses

  1. Lipit Birikiminde Rol Alan Seipin Proteinin Kolesterol İle İndüklenen Yağlı Karaciğer Modelinde Endoplazmik Retikulum Stres ve Otofaji Üzerine Etkisi, 2023.

Academic Activities > Publications

(Scopus) Toplam: 65

Vitamin E: Emerging aspects and new directions

Free Radical Biology and Medicine (2016)

The effect of Irisin on antioxidant system in liver

Free Radical Biology and Medicine (2014)

CD36 as a biomarker of atherosclerosis

Free Radical Biology and Medicine (2014)

Regulation of protein turnover by heat shock proteins

Free Radical Biology and Medicine (2014)

Molecular Function of Tocopherols in Age Related Diseases

Current Pharmaceutical Design (2014)

Resveratrol: French Paradox Revisited

Frontiers in Pharmacology (2012)

Vitamin E mediated response of smooth muscle cell to oxidant stress

Diabetes Research and Clinical Practice (1999)

Signalling functions of α-Tocopherol in smooth muscle cells.

International Journal for Vitamin and Nutrition Research (1997)

d-α-tocopherol control of cell proliferation

Molecular Aspects of Medicine (1993)

Studies on lymphocyte cell surface in ataxia-telangiectasia

Clinical and Experimental Immunology (1985)

Academic Activities > Publications

(Other Scientific Publications) Toplam: 19

Hiperkolesterolemi ve Alzheimer Hastalığı

Turkiye Klinikleri Journal of Medical Sciences (2008)

Vitamins and Regulation of Gene Expression.

Bibliotheca Nutritio et Dieta (2001)

Vitamins and Regulation of Gene Expression

Forum of Nutrition (2001)

α-tocopherol as a modulator of smooth muscle cell proliferation

Prostaglandins, Leukotrienes and Essential Fatty Acids (1997)

Vitamin E: a sensor and an information transducer of the cell oxidation state

The American Journal of Clinical Nutrition (1995)

New roles of low density proteins and vitamin E in the pathogenesis of atherosclerosis

Biochemistry and Molecular Biology International (1995)

Lymphocyte γ-glutamyltranspeptidase activity in ataxia-telangiectasia

Biochemical Medicine and Metabolic Biology (1986)

Academic Activities > Editörlük

  1. Metabolism Clinical and Experimental, ISBN:The ISSN of Metabolism: Clinical and Experimental journal is 00260495, 15328600., 2015.
  2. NFS Journal, ISBN:ISSN: 23523646, 2015.
  3. IUBMB Life, ISBN:ISSN 1521-6551, 2020.
  4. FEBS Open Bio, ISBN:2211-5463, 2024.
  5. IUBMB Life, ISBN:1521-6551, 2024.
  6. FEBS Open Bio, ISBN:2211-5463, 2024.

Projects > Projects

  1. Alfa-13-COOH yüklü makrofaj hedefli nanopartikül etkinliğinin yağlı karaciğer hastalığında incelenmesi, 2027.
  2. Alfa-13-COOH Yüklü Makrofaj Hedefli Nanopartikül Etkinliğinin Yağlı Karaciğer Hastalığında Incelenmesi”, 2027.
  3. Yüksek kolesterol içeriğine sahip fruktoz palmitat ve trans-yağ diyeti ile indüklenen Non-Alkolik Yağlı Karaciğer hastalığından Steatohepatite geçişte ferroptozisin rolünün in vivo olarak incelenmesi, 2025.
  4. SREBP1c inhibisyonunun fruktoz ile indüklenen lipit birikimine etkisinin hepatositlerde belirlenmesi, 2025.
  5. SREBP1c İinhibisyonunun fruktoz ile indüklenen lipit birikimine etkisinin hepatositlerde belirlenmesi, 2025.
  6. Kolesterol ile indüklenen in vitro lipit birikimi ve in vivo NASH modellerinde NRF-2 aktivasyonunun etkisi, 2026.
  7. Kolesterol ile İndüklenen İn vitro lipit birikimi ve in vivo NASH modellerinde Nrf-2 aktivasyonunun etkisi, 2026.
  8. Garsinoik Asit ve 17-oxo-DHA'nın Inflamasyona Karşı Etkinliğinin In Vitro ve In Vivo Modeller Kullanılarak Değerlendirilmesi, 2024.
  9. Seipin Proteinin Yüksek Kolesterollü Diyet ile Indüklenen Yağlı Karaciğer Hastalığındaki Rolünün Saptanması, 2024.
  10. Seipin Proteinin Yüksek Kolesterollü Diyet ile İndüklenen Yağlı Karaciğer Hastalığındaki Rolünün Saptanması, 2024.

Academic Activities > Congress - Conference Participation

  1. Redox Biology: A Paradigm of the Foundation of Life, Serbian Society for Mitocondrial and Free Radical Physiology, 2024.
  2. Annual Meeting of SFRR-E 2024 From Molecules to Tissues: Redox Biology in Action, 2024.
  3. SFRR-E Annual Meeting 2024 “From Molecules To Tissues: Redox Biology In Action, 2024.
  4. SFRR-E Annual Meeting 2024 “From Molecules To Tissues: Redox Biology In Action, 2024.
  5. SFRR-E Annual Meeting 2024 “From Molecules To Tissues: Redox Biology In Action, 2024.
  6. SFRR-E Annual Meeting 2024 “From Molecules To Tissues: Redox Biology In Action, 2024.
  7. SFRR-E Annual Meeting 2024 “From Molecules To Tissues: Redox Biology In Action, 2024.
  8. 4 th BenBedPhar Meeting From Physiology to Pathology, 2023.
  9. 10th Biennial Meeting of Society for Free Radical Research-Asia, “New Paradigm for Research on Oxidative Stress and Inflammation”,, 2022.
  10. 10th Biennial Meeting of Society for Free Radical Research-Asia, “New Paradigm for Research on Oxidative Stress and Inflammation”, 2022.
  11. 10th Biennial Meeting of Society for Free Radical Research-Asia, “New Paradigm for Research on Oxidative Stress and Inflammation”, 2022.
  12. The Korean Academy of Science and Technology, 53th symposium on ‘New Insights on the Landscape of Redox Signaling in Human Diseases, 2022.

Administrative Activities

  1. Merkez Müdürü / Head of Resarch Center, METİFLAM, (2024 - Devam ediyor.)
  2. Kurul Üyeliği / Board Member, FİHADEK, (2024 - Devam ediyor.)

Education and Training Activities