Antibiotic Resistance, Industrial Biotechnology, Omic Technologies, Metabolic Engineering, Protein Engineering
ORCID: 0000-0001-6618-0487
Research Fields
UN Sustainable Development Goal Labels Matching with Research Fields
Short CV
Fatma Gizem Avci received her B.Sc. (2010) and M.Sc. (2013) degrees from the Department of Bioengineering, Ege University. During her M.Sc. studies, she focused on the production of 1,3-propanediol (1,3-PDO) using a cell recycle bioreactor. She received a scholarship from Erasmus Exchange Programme and participated in a project on the production of 1,3-PDO using the metabolic engineering approach for 3 months at the Centre for Industrial Biotechnology and Biocatalysis, Ghent University, Belgium. She completed her Ph.D. at the Department of Bioengineering, Marmara University in 2018. Her research during her Ph.D. was mainly focused on antibiotic resistance mechanisms, investigation of antimicrobial candidates specifically from plant-derived compounds, and understanding their mechanism of action. With support from of FEMS Research Fellowship, she also carried out studies on the characterization of bacterial membrane proteins at the National Scientific Research Center (CNRS-Centre National de la Recherche Scientifique) in Lyon, France.
Fatma Gizem Avci is currently an Assistant Professor at Uskudar University, Bioengineering Department, Turkey. Her research areas include antibiotic resistance, protein engineering, metabolic engineering, omic technologies, and industrial biotechnology.
Education Status & Academic Titles
Supervised Graduate Theses
- Investigation of the Antivirulence Agents Targeting the Type IV Pili, 2023.
Academic Activities > Publications
(Scopus) Toplam: 16Attenuation of Type IV pili activity by natural products
Journal of Biomolecular Structure and Dynamics (2024)
A review on the mechanistic details of OXA enzymes of ESKAPE pathogens
Pathogens and Global Health (2022)
Carvacrol Enhances the Antimicrobial Potency of Berberine in Bacillus subtilis
Current Microbiology (2022)
Targeting a hidden site on class A beta-lactamases
Journal of Molecular Graphics and Modelling (2018)
An OMIC approach to elaborate the antibacterial mechanisms of different alkaloids
Phytochemistry (2017)
An evolutionarily conserved allosteric site modulates beta-lactamase activity
Journal of Enzyme Inhibition and Medicinal Chemistry (2016)
1, 3-propanediol production with Citrobacter werkmanii DSM17579: effect of a dhaD knock-out
Microbial Cell Factories (2014)
The effects of cell recycling on the production of 1, 3-propanediol by Klebsiella pneumoniae
Bioprocess and Biosystems Engineering (2013)
Academic Activities > Publications
(Other Scientific Publications) Toplam: 2Curvularia lunata: A fungus for possible berberine transformation
International Journal of Secondary Metabolite (2022)
Evaluation of silibinin as an efflux pump inhibitor in Bacillus subtilis
International Journal of Secondary Metabolite (2021)
Academic Activities > Book - Book Chapter
(Other) Toplam: 3- Modeling the Microbial Cells for Biotechnological Applications, 2023.
- Antibacterial and antifungal activities of isoquinoline alkaloids of the Papaveraceae and Fumariaceae families and their implications in structure–activity relationships, 2021.
- Fermente Ürünler Teknolojisi ve Mikrobiyolojisi- Antibiyotik Üretimi, 2020.
Projects > Projects
- ESKAPE patojenlerinde yaygın bulunan D-sınıfı beta-laktamazlara karşı ortak inhibitörlerin belirlenmesi, 2026.
- Tip 4 pili protein kompleksinin inhibisyonu ve inhibisyon dinamiğinin karakterizasyonu, 2023.
Academic Activities > Congress - Conference Participation
- 47th FEBS Congress, 2023.
- 8th International BAU Drug Design Congress, 2022.
- 4th Eurasia Biochemical Approaches & Technologies Congress (EBAT), 2022.
- FEMS Conference on Microbiology 2022, 2022.
- 9. Ulusal Moleküler Biyoloji ve Biyoteknoloji Kongresi, 2020.
- MuTaLig COST ACTION CA15135 4th WG meeting, 2020.
Administrative Activities
- Öğrenci Danışmanlığı / Student Adviser, 41-50 Öğrenci Danışmanlığı, (2023 - 2024)
- Ana Bilim Başkanı / Head of Department, Biyomühendislik, (2022 - 2024)
- Bölüm Başkanlığı / Head of Department, Biyomühendislik (İngilizce), (2022 - 2024)
- Laboratuvar, Laboratuvar Sorumlusu, (2022 - 2024)
- Kurul Üyeliği / Board Member, Fakülte Kurulu Üyeliği, (2022 - 2024)
- Çalışma Grubu Koordinatörlüğü / Coordinator of Research Group, Biyomühendislik Çalışma Grubu, (2022 - 2024)
- Koordinatör / Coordinator, ARGEYEP Koordinatörlüğü (Enstitü / Fakülte / MYO), (2022 - 2024)
- Koordinatör / Coordinator, Erasmus Koordinatörlüğü (Enstitü / Fakülte / MYO), (2022 - 2024)
- Kurul Üyeliği / Board Member, Enstitü Kurulu Üyeliği, (2022 - 2024)
- Komisyon Üyesi / Member of Commission, Bologna Komisyonu, (2022 - 2024)
- Öğrenci Danışmanlığı / Student Adviser, 31-40 Öğrenci Danışmanlığı, (2022 - 2023)
- Komisyon Üyesi / Member of Commission, Mezuniyet Komisyonu (Enstitü / Fakülte / MYO), (2022 - 2024)
- Bölüm Başkan Yardımcısı / Deputy Head of Department, Biyomühendislik (İngilizce) Bölüm Başkan Yardımcısı, (2021 - 2022)
- Çalışma Grubu Üyelikleri / Research Group Membership, Biyomühendislik Çalışma Grubu, (2020 - Devam ediyor.)
- Öğrenci Danışmanlığı / Student Adviser, 41-50 Öğrenci Danışmanlığı, (2019 - 2022)
- Komisyon Üyesi / Member of Commission, Eğitim Komisyonu (Enstitü / Fakülte / MYO), (2019 - 2021)
- Komisyon Üyesi / Member of Commission, Staj Komisyonu (Enstitü / Fakülte / MYO), (2019 - 2021)
- Komisyon Üyesi / Member of Commission, Kalite Komisyonu (Enstitü / Fakülte / MYO), (2019 - 2022)