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Molecular Biology and Genetics Laboratory

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Operating under the Department of Molecular Biology and Genetics at Üsküdar University, the Molecular Biology and Genetics Laboratory is an advanced research and application center where scientific production is carried out in compliance with global standards in the fields of biotechnology, genetics, and microbiology.

What is the Molecular Biology and Genetics Laboratory? / What is its Purpose?

Main Purpose: The primary purpose of the Molecular Biology and Genetics Laboratory is to develop new products and services needed by the industry, contribute to molecular biology-based R&D and innovation studies in our country, and design new scientific methods to be placed at the service of humanity. The laboratory centers its focus on conducting interdisciplinary and multidisciplinary research aimed at establishing high-value-added collaborations between the university and industry. At the same time, it resolutely continues its infrastructure development efforts aimed at protecting human and environmental health and solving existing biological problems.

Devices and Technical Equipment Available in the Laboratory

Salient Features: The laboratory infrastructure has been structured with high-technology device equipment to perform sensitive analyses at the cellular, microbial, and genetic levels, DNA manipulations, and biotechnological syntheses. The technical equipment that enables the molecular processes carried out in the laboratory to be monitored with high accuracy includes:

  • Molecular Analysis and Genomic Equipment: High-precision amplification systems that enable the amplification of genetic material during preparation processes prior to polymorphism, genotyping, and DNA sequencing.
  • Genetic Engineering and Recombinant Infrastructure: Nucleic acid purification systems and electrophoresis units used in plasmid isolation, cloning, and gene transfer processes within the scope of recombinant DNA technologies.
  • Microbiology and Culture Equipment: Controlled incubators and deep-freezer storage units that ensure microorganisms and cell lines are incubated, propagated, and preserved under sterile conditions in microbial biotechnology studies.
  • Sterilization and Bio-Security Systems: Bio-security cabinets and advanced sterilization devices that reduce risks to human and environmental health to zero and prevent intra-laboratory contamination.

Research Areas and Application Areas

Academic Contribution: The laboratory offers a wide spectrum of research opportunities to the department's academic staff, graduate students, and undergraduate students participating in research projects. The main study and research areas actively carried out in the laboratory are:

  • Human Genetics and Polymorphism: Detection of genetic variations in the human genome, polymorphisms, and molecular mechanisms of hereditary diseases.
  • Recombinant DNA Technologies: Gene cloning, vector design, recombinant protein production, and genetic engineering applications.
  • Microbiology: Studies on the isolation, identification, and physiological and molecular characterization of microorganisms.
  • Biotechnology and Microbial Biotechnology: R&D processes for developing biotechnological products, enzymes, and metabolites of industrial value using microorganisms.
  • Environmental and Human Health Research: Bioremediation strategies aimed at solving environmental problems and protective/preventive molecular solutions safeguarding human health.

Contributions to Students and the Industry

  • Early-Stage Professional Experience: Students of the Department of Molecular Biology and Genetics gain direct professional and experimental experience by actively participating in laboratory practices and ongoing research projects starting from the second year of their education (sophomore year).
  • Industrial Innovation Support: It directly contributes to domestic production and industry by designing molecular solutions to meet the industry's growing innovation and product development needs.
  • Graduate Research Base: It provides graduate students at the master's and doctoral levels with an advanced research environment at international standards for their thesis studies and independent projects.
  • Multidisciplinary Working Culture: Through the interdisciplinary and multidisciplinary projects carried out within its body, it enhances the ability of researchers and students to speak a common language and produce joint solutions across different branches of science.

Frequently Asked Questions

Inventory

DEVICE TYPE and LICENSED SOFTWAREQUANTITY
Real Time PCR/Roche-Light Cycler1
Biosafety cabinet/Thermo Scientific1
Incubator/Thermo Scientific1
Gel Imaging/Fusion FX7-021
Dry block heater/Stuart-03SBH1301
Liquid nitrogen tank/Bio Cane Canister Thermo1
Refrigerated incubator/Thermo Q4000-041
Orbital shaking incubator/Thermo1
Hotplate magnetic stirrer/Thermo1
Non-refrigerated centrifuge/Thermo SL16 230 V1
Spectrophotometer-Elisa Reader/Thermo Multiskan 200-1000nm1
Western Blot System/Thermo Pierce1
Distilled water system/Smart2 Pure 31
Vortex/Stuart1
Horizontal Electrophoresis/Thermo1
Moleküler Biyoloji ve Genetik Laboratuvarı - Görsel 213 - 1Moleküler Biyoloji ve Genetik Laboratuvarı - Görsel 214 - 2Moleküler Biyoloji ve Genetik Laboratuvarı - Görsel 215 - 3Moleküler Biyoloji ve Genetik Laboratuvarı - Görsel 216 - 4Moleküler Biyoloji ve Genetik Laboratuvarı - Görsel 217 - 5Moleküler Biyoloji ve Genetik Laboratuvarı - Görsel 218 - 6Moleküler Biyoloji ve Genetik Laboratuvarı - Görsel 219 - 7Moleküler Biyoloji ve Genetik Laboratuvarı - Görsel 220 - 8

Videos

Research Activities

Projects

  • Diyabetik HaCaT Hücre Modelinde Kafur ve Çay Ağacı Yağının Yara İyileşmesini Düzenleyen Mekanizmalar Üzerine Etkisinin Araştırılması

    Category: TÜBİTAK

    Application No: 1006894

    Date: 2026-09-23

  • Bifonksiyonel Katalaz-Fenol Oksidaz Enzimi Tabanlı Nanoformülasyonların Meme Kanseri Hücrelerinde Terapötik Etkinliğinin in vitro İncelenmesi

    Category: TÜBİTAK

    Application No: 995052

    Date: 2026-09-10

  • Yeşil Limon Kabuklarından (Citrus limon) Elde Edilen Fenilalanin Amonyum Liyaz Enziminin Kısmi Saflaştırılması Karakterizasyonu ve Biyopolimer Matrislerde İmmobilizasyonunun Araştırılması

    Category: Diğer Ulusal Kamu Kuruluşları

    Application No: 7971

    Date: 2026-10-27

Publications
Publications indexed in Scopus: 23Number of Other Publications: 16

Books

Congresses Attended

  • Microgravity-Induced Rewiring of Longevity and Mechanotransduction Networks in Human Immune Cells During the MESSAGE Science Mission

    Conference Name: Uluslararası kongre ve sempozyumlarda sözlü olarak sunulan ve özet metin olarak yayımlanan tebliğ

    Date: 2026-10-09

    Participants:Dr. Öğr. Üyesi Cihan TAŞTAN Beyza AYDIN

  • A Microgravity-Responsive Cellular Axis of Glucose Metabolism Adaptation in Astronaut Peripheral Blood Mononuclear Cells

    Conference Name: Uluslararası kongre ve sempozyumlarda sözlü olarak sunulan ve özet metin olarak yayımlanan tebliğ

    Date: 2026-10-09

    Participants:Dr. Öğr. Üyesi Cihan TAŞTAN Beyza AYDIN

  • Persistent Oncogene and Tumor Suppressor Gene Dysregulation Under Sustained Microgravity Exposure

    Conference Name: Uluslararası kongre ve sempozyumlarda sözlü olarak sunulan ve özet metin olarak yayımlanan tebliğ

    Date: 2026-10-08

    Participants:Dr. Öğr. Üyesi Cihan TAŞTAN Beyza AYDIN

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Creation Date: January 08, 2025