Endoplazmik retikulum stress, Lipit birikimi, Yüksek yağlı diyet, Yağlı karaciğer hastalığı, Metabolik hastalıklar
tugce.demirelyalciner
uskudar.edu.tr
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ORCID: 0000-0002-6540-882X
Documents : 11 | Citation : 152 | h-index : 5
Citation : 68 | h-index : 5 | i10-index : 3
Araştırma Alanları
Araştırma Alanları İle Örtüşen BM Sürdürülebilir Kalkınma Hedef Etiketleri
Kısa Özgeçmiş
Lisans eğitimimi 2015 yılında İstanbul Kültür Üniversitesi Moleküler Biyoloji ve Genetik bölümünde tamamladım. Yüksek lisans eğitimimi Marmara Üniversitesi Tıp Fakültesi Tıbbi Biyokimya Anabilim dalında 2017 yılında tamamladıktan sonra aynı bölümde 2023 yılında doktora eğitimini tamamladım. Yüksek lisans ve doktora eğitimim boyunca yaptığım metobolik hastalıklar ve yağlı karaciğer hastalığı alanlarında TÜBİTAK destekli projeler ve yayınlarım bulunmaktadır.
Öğrenim Durumu & Akademik Unvanlar
2015
Lisans
İstanbul Kültür Üniversitesi Moleküler Biyoloji ve Genetik
2017
Yüksek Lisans
Marmara Üniversitesi Tıbbi Biyokimya
2023
Doktora
Marmara Üniversitesi Tıbbi Biyokimya
Akademik Faaliyetler > Yayınlar
(Scopus) Toplam: 9Modulation of inflammatory signaling by vitamin E metabolites and its therapeutic implications
Free Radical Research (2025)
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Free Radical Research (2024)
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Mechanisms of Ageing and Development (2024)
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Free Radical Biology and Medicine (2022)
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Endoplasmic Reticulum Stress and miRNA Impairment in Aging and Age-Related Diseases
Frontiers in Aging (2022)
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High cholesterol diet activates ER stress mediated apoptosis in testes tissue: Role of α-tocopherol
IUBMB LIFE (2021)
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BioFactors (2020)
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Cholesterol induced autophagy via IRE1/JNK pathway promotes autophagic cell death in heart tissue
Metabolism (2020)
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Vitamin E: Regulatory role in the cardiovascular system
IUBMB Life (2019)
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Akademik Faaliyetler > Yayınlar
(Diğer Bilimsel Yayınlar) Toplam: 3Projeler > Projeler
- Alfa-13-COOH yüklü makrofaj hedefli nanopartikül etkinliğinin yağlı karaciğer hastalığında incelenmesi, 2027.
- Alfa-13-COOH Yüklü Makrofaj Hedefli Nanopartikül Etkinliğinin Yağlı Karaciğer Hastalığında Incelenmesi”, 2027.
- SREBP1c inhibisyonunun fruktoz ile indüklenen lipit birikimine etkisinin hepatositlerde belirlenmesi, 2025.
- SREBP1c İinhibisyonunun fruktoz ile indüklenen lipit birikimine etkisinin hepatositlerde belirlenmesi, 2025.
- Kolesterol ile indüklenen in vitro lipit birikimi ve in vivo NASH modellerinde NRF-2 aktivasyonunun etkisi, 2026.
- Kolesterol ile İndüklenen İn vitro lipit birikimi ve in vivo NASH modellerinde Nrf-2 aktivasyonunun etkisi, 2026.
- Seipin Proteinin Yüksek Kolesterollü Diyet ile Indüklenen Yağlı Karaciğer Hastalığındaki Rolünün Saptanması, 2024.
- Seipin Proteinin Yüksek Kolesterollü Diyet ile İndüklenen Yağlı Karaciğer Hastalığındaki Rolünün Saptanması, 2024.
Akademik Faaliyetler > Kongre - Konferans Katılım
- Redox Biology: A Paradigm of the Foundation of Life, Serbian Society for Mitocondrial and Free Radical Physiology, 2024.
- Annual Meeting of SFRR-E 2024 From Molecules to Tissues: Redox Biology in Action, 2024.
- SFRR-E Annual Meeting 2024 “From Molecules To Tissues: Redox Biology In Action, 2024.
- SFRR-E Annual Meeting 2024 “From Molecules To Tissues: Redox Biology In Action, 2024.
İdari Faaliyetler
- Merkez Müdür Yardımcısı / Deputy Head of Research Center, METİFLAM Müdür Yardımcısı, (2024 - Devam ediyor.)
Eğitim ve Öğretim Faaliyetleri
- Volunteering Work, (Lisans / 2023-2024 Bahar)
- Biyokimya, (Lisans / 2023-2024 Güz)