Dr.Öğr. Üyesi Doğukan MUTLU

MDBF / Moleküler Biyoloji ve Genetik (Türkçe) Bölüm Başkan Yardımcısı

dogukan.mutluuskudar.edu.tr

(0216) 400 2222 / 2490

ORCID: 0000-0003-3259-5822

Documents : 32 | Citation : 166 | h-index : 8

Citation : 253 | h-index : 9 | i10-index : 9

: 22
: 1

Araştırma Alanları

Biyokimya, Hücre Biyolojisi, Kanser Biyolojisi, Moleküler Genetik, Biyoinformatik

Araştırma Alanları İle Örtüşen BM Sürdürülebilir Kalkınma Hedef Etiketleri

3

Kısa Özgeçmiş

Doğukan Mutlu 1989 yılında İstanbul'da doğdu. Lisans eğitimini 2012 yılında Pamukkale Üniversitesi Biyoloji Bölümünde tamamladı. Yüksek lisans derecesini 2015 yılında Pamukkale Üniversitesi Biyoloji Anabilim Dalında aldı. Yüksek lisans çalışmaları sırasında TÜBİTAK tarafından finanse edilen farklı projelerde görev aldı. 2018'de Pamukkale Üniversitesi Biyoloji Anabilim Dalında başladığı doktora eğitimini 2022 yılında tamamladı. Doktorası sırasında insan kanser hücre hatlarında ve patojenik mikroorganizmalarda sentezlenmiş bileşiklerin, çeşitli aktif fitokimyasalların ve doğal polisakkaritlerin antikanser ve antimikrobiyal aktiviteleri üzerine araştırmalar yaptı.

Devamı

Öğrenim Durumu & Akademik Unvanlar

2012

Lisans

Pamukkale Üniversitesi Biyoloji

2015

Yüksek Lisans

Pamukkale Üniversitesi Biyoloji

2022

Doktora

Pamukkale Üniversitesi Biyoloji

Akademik Faaliyetler > Yayınlar

(Scopus) Toplam: 31

New cyclometalated iridium(III) complexes bearing substituted 2-(1H-benzimidazol-2-yl)quinoline: Synthesis, characterization, electrochemical and anticancer studies

Bioorganic Chemistry (2024)

Polyacrylonitrile (PAN)/carbon nanotube (CNT) electrospun nanofibers: synthesis, characterization, their biocompatibility for L929 fibroblast cells and molecular docking studies

International Journal of Polymeric Materials and Polymeric Biomaterials (2024)

Half-Sandwich Ru(II) Complexes Bearing 2-(2'-quinoly)benzimidazoles with Anticancer Activity

Biointerface Research in Applied Chemistry (2024)

Cytotoxic and Apoptosis-Inducing Activities of Iridium Complexes Bearing 2-Phenylimidazo[4,5-f][1,10]-Phenanthroline Derivatives in Human Cancer Cells

Pharmaceutical Chemistry Journal (2024)

Evaluation of Anti-Biofilm and in Vitro Wound Healing Activity of Bacterial Cellulose Loaded with Nanoparticles and Borax

Journal of Polymers and the Environment (2024)

Evaluation of Antibiofilm and Cytotoxic Activity of Microalgae Isolated from Different Sites of betwata- Erbil/Iraq

Baghdad Science Journal (2024)

Biosourced polymeric cryogels for future biomedical applications with remarkable antimicrobial activities and tribological properties

Materials Today Communications (2024)

Biological activities of Liquidambar orientalis: Antibiofilm, cytotoxicity, apoptosis, and miRNA expressions

Botanica Serbica (2024)

Exploring 2-Pyrazoline derivatives as potent antidiabetic agents and cholinesterase inhibitors: Their synthesis and molecular docking studies

Journal of Molecular Structure (2024)

Evaluation of the effect of injectable platelet-rich fibrin (i-PRF) in wound healing and growth factor release in rats: a split-mouth study

Growth Factors (2024)

Investigation of controlled drug release of ibuprofen with prepared and characterized innovative bigel materials

Wiley (2023)

Evaluating Antibiofilm, Cytotoxic and Apoptotic Activities of Scutellaria brevibracteata subsp. brevibracteata Essential Oil

Chemistry and Biodiversity (2023)

Fusaric acid inhibits cell proliferation and downregulates expressions of toll-like receptors pathway genes in Ishikawa endometrial cancer cells

European Review for Medical and Pharmacological Sciences (2023)

PHEMA/PPy cytocompatible conductive cryogels: One-pot synthesis, characterization, and electrical properties

Elsevier BV (2023)

Assessing effects of caffeic acid on cytotoxicity, apoptosis, invasion, GST enzyme activity, oxidant, antioxidant status and micro-RNA expressions in HCT116 colorectal cancer cells

Elsevier BV (2023)

The anticancer effect of Salvia pisidica essential oil through promotion intrinsic and extrinsic apoptosis pathways in human cancer cell lines

Journal of Herbal Medicine (2023)

In Vitro Evaluation of Cytotoxic Activity of Algerian propolis against HumanBreast Adenocarcinoma (MDA-MB-231) Cells and Investigation of itsPotential Mechanism of Action

Bentham Science Publishers Ltd. (2023)

Synthesis, Characterization, Antibiofilm and Anticancer Activity of NewRuthenium Complexes with 2,2-bipyridine-4,4-dicarboxamide

Letters in Organic Chemistry (2022)

New cytotoxic chalcone derivatives from Astragalus ponticus Pall.

Natural Product Research (2022)

Design, synthesis and pharmacological evaluation of novel Artemisinin-Thymol

Natural Product Research (2022)

Synthesis of water soluble symmetric and asymmetric pillar[5]arene derivatives: Cytotoxicity, apoptosis and molecular docking studies

Journal of Molecular Structure (2022)

Synthesis and biological activity of new indole based derivatives as potent anticancer, antioxidant and antimicrobial agents

Journal of Molecular Structure (2022)

A Novel 4H-Chromen-4-One Derivative from Marine Streptomyces ovatisporus S4702T as Potential Antibacterial and Anti-Cancer Agent

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2022)

Anticancer and apoptotic effects of a polysaccharide extract isolated from Lactarius chrysorrheus Fr. in HepG2 and PANC-1 cell lines

Archives of Biological Sciences (2022)

A Thiophene Derivative, 2-Bromo-5-(2-(methylthio)phenyl)thiophene, Has Effective Anticancer Potential with Other Biological Properties

ChemistrySelect (2022)

Identification of 3-Bromo-1-Ethyl-1H-Indole as a Potent Anticancer Agent with Promising Inhibitory Effects on GST Isozymes

Anti-Cancer Agents in Medicinal Chemistry (2021)

Synthesis, Cytotoxicity, Antioxidant and Antimicrobial Activity of Indole Based Novel Small Molecules

LETTERS IN DRUG DESIGN & DISCOVERY (2021)

New iridium bis-terpyridine complexes: synthesis, characterization, antibiofilm and anticancer potentials

BioMetals (2021)

Assessment of Cytotoxic and Apoptotic Effects of Salvia syriaca L. in Colorectal Adenocarcinoma Cell Line (Caco-2)

IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (2021)

Synthesis, Biological Evaluation and Molecular Docking of Novel Thiophene\u2010Based Indole Derivatives as Potential Antibacterial, GST Inhibitor and Apoptotic Anticancer Agents

ChemistrySelect (2020)

Comparative study of antibiofilm, cytotoxic activity and chemical composition of Algerian propolis

Journal of Apicultural Research (2019)

Akademik Faaliyetler > Yayınlar

(Diğer Bilimsel Yayınlar) Toplam: 6

Phenolic Acids Modulating Epigenetic Mechanisms in HepG2 Human Hepatoma Cells

Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi (2024)

Expression of sialic acid binding receptors (siglecs) in human trophoblast cell line

Pamukkale Tıp Dergisi (2024)

Functional Food Components and Activities of Pinus nigra and Pinus sylvestris Barks as Food Supplements

International Journal of Chemistry and Technology (2023)

Anticancer Effects of Alpha-lipoic Acid on A172 and U373 Human Glioblastoma Cells

Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi (2023)

Effects of Usnic Acid on Cytotoxicity, Colony Formation and Migration in SK-UT-1 Human Uterine Leiomyosarcoma Cells

Süleyman Demirel Üniversitesi Fen Edebiyat Fakültesi Fen Dergisi (2023)

In Vitro Regulation of the Expression of the Sars-Cov-2 Receptor Angiotensin-Converting Enzyme (Ace2) in Lung Cancer Cells by Natural Products

Trakya University Journal of Natural Sciences (2021)

Akademik Faaliyetler > Kitap - Kitap Bölümü

(Diğer) Toplam: 1
  1. Kanser tedavisi için arı zehri ve melittin’in terapötik potansiyeli, Sevki Arslan, Dogukan Mutlu, Türkiye Klinikleri, 2021

Akademik Faaliyetler > Editörlük

  1. Düzce Üniversitesi Bilim ve Teknoloji Dergisi, ISBN:2148-2446, 2024.

Akademik Faaliyetler > Kongre - Konferans Katılım

  1. 5th International Selcuk Scientific Research Congress, 2024.
  2. 12th Aegean Analytical Chemistry Days, 2023.
  3. 6th International Eurasian Conference on Biological and Chemical Sciences, 2023.
  4. 3rd International Mediterranean Scientific Research and Innovation Congress, 2023.
  5. 3rd International Congress on Contemporary Scientific Research, 2023.
  6. 7th International Conference on Medical & Health Sciences, 2023.
  7. 5th International Eurasian Conference on Biological and Chemical Sciences, 2022.
  8. 3rd International Congress on Plant Biology., 2022.
  9. 7th International Mediterranean Symposium on Medicinal and Aromatic Plants, 2021.
  10. 32. Ulusal Kimya Kongresi, 2020.
  11. 4rd International Symposium on EuroAsian Biodiversity, 2018.
  12. 4rd International Symposium on EuroAsian Biodiversity, 2018.
  13. 4rd International Symposium on EuroAsian Biodiversity, 2018.
  14. 4rd International Symposium on EuroAsian Biodiversity, 2018.
  15. 9th Congress of the Turkish Toxicology Society, 2015.
  16. 35th Annual Symposium on Sea Turtle Biology and Conservation, 2015.

İdari Faaliyetler

  1. Bölüm Başkan Yardımcısı / Deputy Head of Department, Moleküler Biyoloji ve Genetik (Türkçe) Bölüm Başkan Yardımcısı, (2024 - Devam ediyor.)
  2. Öğrenci Danışmanlığı / Student Adviser, 51-60 Öğrenci Danışmanlığı, (2024 - Devam ediyor.)
  3. Komisyon Üyesi / Member of Commission, Staj Komisyonu (Enstitü / Fakülte / MYO), (2024 - Devam ediyor.)
  4. Komisyon Üyesi / Member of Commission, Erasmus ve Dış İlişkiler Komisyonu, (2024 - Devam ediyor.)