It carries out research to improve the biological activity of natural products, newly synthesized compounds and their derivatives with different side groups by chemoinformatics methods. The aim of the working group is to change the effect profile of molecules by manipulating their chemical structure and to increase their existing efficacy. These studies aim to bring innovative approaches to modern drug development processes and to reveal more effective treatment strategies.
Precursor Drug Molecules Research Working Group
Research Focus
MeetingsLast 5 Meetings
Öncül İlaç Molekülleri Araştırma Grubu
Projects
Morfin Bağımlılığıyla Mücadele ve Nöroprotektif Etkilerin Artırılması için GPCR İlaç Keşfinde Yeni Eğilimler: Apelin/APJ Sisteminin Rolü
Category: Diğer Ulusal Kamu Kuruluşları
Application No: TOA-2026-38657
Date: 2026-01-13
PublicationsNumber of Publications Indexed in WOS: 8Number of Other Publications: 2
- Evaluation Of Boron's Anticancer Effect
Publication Title: Bor Dergisi
DOI: 10.30728/boron.1829292
Date: 2026-03-31
Authors:Arş. Gör. Seda KUŞOĞLU GÜLTEKİNArş. Gör. Şeyma YEKTARArş. Gör. İrem OLGUN ACAR
- Usnic acid induces apoptosis and inhibits cell migration and invasion in hepatocarcinoma cells: in vitro and in silico analysis
Publication Title: BMC Complementary Medicine and Therapies
DOI: 10.1186/s12906-026-05354-x
Date: 2026-03-23
Authors:Dr. Öğr. Üyesi Doğukan MUTLU
- Phytochemical analysis and anticancer activities of the essential oil from Cedrus libani A. Rich. cones in A375 human melanoma cells
Publication Title: Natural Product Research
DOI: 10.1080/14786419.2026.2614396
Date: 2026-01-10
Authors:Dr. Öğr. Üyesi Doğukan MUTLU
Conference Participations
Effects of 2-hydroxycinnamic acid on cell viability and apoptosis in human ovarian cancer cell lines SK-OV-3 and OVCAR-3
Conference Name: Uluslararası kongre ve sempozyumlarda sözlü olarak sunulan ve özet metin olarak yayımlanan tebliğ
Date: 2024-12-14
Participants:Dr. Öğr. Üyesi Doğukan MUTLU
Phytochemical Constituents and Antileukemic Effects of Juniperus oxycedrus Extract
Conference Name: Uluslararası kongre ve sempozyumlarda sözlü olarak sunulan ve özet metin olarak yayımlanan tebliğ
Date: 2025-02-27
Participants:Prof. Dr. Belkıs ATASEVER ARSLANArş. Gör. Seda KUŞOĞLU GÜLTEKİNArş. Gör. İrem Gülfem AKIN
Other Activities
DHA'da yayınlanan "Epilepsi tedavisinde karbon kuantum noktalarıyla umut veren çalışma" başlıklı haber
Category: Detaylı Medya Katılımı
Date: 2026-01-29
Participants: Prof. Dr. İ. Tayfun UZBAY
Members
Asst. Prof. Doğukan MUTLUFENS / Department of Molecular Biology and Genetics / Head of the Department of Biotechnology at the Graduate School of Sciences / Director of the Distance Education Application and Research Center (ÜSUZEM) / Distance Education Coordinator
- RA (Ph.D.) İrem Gülfem AKIN
FENS / Molecular Biology and Genetics (English)
RA Seda KUŞOĞLU GÜLTEKİNFENS / Molecular Biology and Genetics (Turkish)
RA Ayşegül YANIK İLGARFENS / Molecular Biology and Genetics (Turkish)

